Septal penetration correction in I imaging following thyroid cancer treatment. Whole body gamma camera images acquired after I treatment for thyroid cancer can suffer from collimator septal penetration artefacts because of the high energy of the gamma photons. Deconvolution has the potential to reduce such artefacts, by taking into account the non-Gaussian point-spread-function PSF of the system. A Richardson—Lucy deconvolution algorithm, with and without prior scatter-correction was tested as a method of reducing septal penetration in planar gamma camera images. Phantom images hot spheres within a warm background were acquired and deconvolution using a measured PSF was applied.
Septal Penetration and Septal Scatter Response Functions
Septal Penetration and Septal Scatter Response Functions - Nuclear Medicine
Try out PMC Labs and tell us what you think. Learn More. In single photon emission computed tomography, the choice of the collimator has a major impact on the sensitivity and resolution of the system. Traditional parallel-hole and fan-beam collimators used in clinical practice, for example, have a relatively poor sensitivity and subcentimeter spatial resolution, while in small-animal imaging, pinhole collimators are used to obtain submillimeter resolution and multiple pinholes are often combined to increase sensitivity. This paper reviews methods for production, sensitivity maximization, and task-based optimization of collimation for both clinical and preclinical imaging applications. New opportunities for improved collimation are now arising primarily because of i new collimator-production techniques and ii detectors with improved intrinsic spatial resolution that have recently become available. These new technologies are expected to impact the design of collimators in the future.
The septal penetration response function SPRF describes the contribution to the total collimator-detector response by photons that penetrate through the collimator septa. To date there has been no analytic treatment of the septal penetration response for multi-hole collimators. Both of these effects are most important for isotopes emitting medium and high energy photons such as In, Ga, or I
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